Leica Microsystems meets Science: Interview with Timo Zimmermann

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Leica Microsystems meets Science: Interview with Timo Zimmermann

Interview with Timo Zimmermann, CRG-Centre for Genomic Regulation, Barcelona, Spain:

Timo Zimmermann is head of the superior gentle microscopy unit within the middle for genomic regulation in Barcelona that gives entry to the entire vary of excessive and lightweight microscopy gear to different researchers. The primary super-resolution picture he noticed was an eye fixed opener for him: “It was not simply constructions that acquired smaller. I used to be a pattern that I particularly had excessive hopes of seeing one other layer of complexity and this really was there.” The pattern had been a single-cellular marine organism with advanced microtubule construction which might hardly be guessed in a confocal microscope. However the complexity could possibly be revealed by a STED microscope. Timo Zimmermann is enthusiastic concerning the new 3D expertise supplied by the brand new Leica TCS SP8 STED 3X: “The third dimension actually improved the outcomes. It is a bit like evaluating widefield and confocal imaging. Confocal imaging did precisely the identical factor: it lowered data to the related a part of the focal airplane and doing the identical with super-resolution provides comparable results. You may have extra readability in your picture.” The limiting issue of STED for him can be the sunshine price range and he hopes that the event of appropriate dyes will overcome these limitations. With the event of higher and higher industrial super-resolution techniques, Zimmermann is satisfied that super-resolution microscopy will likely be increasingly more seen as an ordinary. “I already began to understand confocal photographs as a bit unsharp. The dots simply could get smaller, however seeing it higher sharpens your notion of the construction.”

For extra data on super-resolution options from Leica Microsystems, please go to:

superresolution microscopy